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Dr Mark McClure

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Dr Mark McClure’s Profile

Dr Mark McClure is a Consultant Nephrologist at Belfast Health and Social Care Trust, specialising in kidney and transplant medicine. He has expertise in a broad range of kidney conditions, including acute kidney injury, chronic kidney disease, hypertension (high blood pressure), kidney stones, glomerulonephritis, vasculitis, and lupus.

Dr McClure graduated in 2008 and completed specialist training in leading kidney and transplant centres in Cambridge and Bristol before joining the Belfast kidney team in 2024. He holds a PhD in Medicine from the University of Cambridge, where his research focused on B cell therapy in ANCA-associated vasculitis. He is also an Honorary Lecturer at Queen’s University Belfast and is actively involved in clinical research and medical education.

Known for his approachable and compassionate manner, Dr McClure combines clinical excellence with a strong commitment to evidence-based practice. He is dedicated to shared decision-making, ensuring that patients and their families are fully involved in their care.

Current NHS/HSE Posts

Consultant Nephrologist at Belfast HSC Trust

Qualifications

  • MBBS, University of Wales, College of Medicine, Cardiff, 2008
  • MRCP 2012
  • MRCP Specialty Certificate Examination in Nephrology / ESENeph, 2022
  • GMC Full Registration No. 7015020
  • PhD in Medicine, University of Cambridge, 2022
  • CCT in Renal and General Internal Medicine, East of England Deanery, 2023

Professional bodies (Positions held in last 3 years)

  • GMC Full Registration No. 7015020
  • MDU Registration No. 460928D

Publications

  • A randomised study of rituximab and belimumab sequential therapy in PR3 ANCA-associated vasculitis (COMBIVAS): design of the study protocol. McClure, M.E, Gopaluni, S, Wason, J. et al. Trials. 2023.
  • Age and time-dependent increase in incident anti-glomerular basement membrane (anti-GBM) disease: a nation-wide cohort study. Karl Emil Nelveg-Kristensen, Bo Madsen, Mark McClure, et al. CKJ. 2023
  • Long-term maintenance rituximab for ANCA-associated vasculitis: relapse and infection prediction Models. Mark E McClure, Yajing Zhu, Rona M Smith, et al. Rheumatology. 2021
  • Treatment of Relapses in ANCA-Associated Vasculitis. McClure M, Jones RB. Clinical Journal of American Society of Nephrology. 2019.
  • Evaluation of PR3-ANCA Status After Rituximab for ANCA-Associated Vasculitis. McClure ME, Wason J, Gopaluni S, et al. Journal of Clinical Rheumatology. 2019
  • B cell therapy in ANCA-associated vasculitis: current and emerging treatment options. McClure M, Gopaluni S, Jayne D, Jones R. Nature Reviews Rheumatology. 2018
  • Long-term graft outcomes and patient survival are lower post-transplant in patients with a primary renal diagnosis of glomerulonephritis. Rishi Pruthi, Mark McClure, Anna Casula, et al. Kidney International 2016

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